help  | about  | cite  | software

Gene : H2BC4 Homo sapiens

Name  ? H2B clustered histone 4 Cytological Location  6p22.2
Brief Description  H2B clustered histone 4
Description  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The protein has antibacterial and antifungal antimicrobial activity. The main transcript variant of this gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. This transcript variant lacks a polyA tail but instead contains a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Apr 2020]
  • synonyms:
  • histone cluster 1, H2bc,
  • H2B histone family, member L,
  • H2B.1,
  • H2BC7,
  • H2B/l,
  • OTTHUMG00000014425,
  • HGNC:4757,
  • H2BFL,
  • H2BC4,
  • histone 1, H2bc,
  • NM_003526,
  • H2BC10,
  • histone cluster 1 H2B family member c,
  • dJ221C16.3,
  • Z80783,
  • uc003ngk.5,
  • H2BC8,
  • HIST1H2BC,
  • H2BC6,
  • H2BFL,
  • H2B.1,
  • HIST1H2BC,
  • H2B/l
  • identifiers:
  • 8347,
  • ENSG00000180596,
  • H2BC4

Genome feature

Region: gene ? Length: 460  
Location: 6:26123467-26123926 reverse strand Cyto location: 6p22.2

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

95 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



95 Pathways

85 SN Ps

4 Cross References

15 Data Sets

0 Homologues

0 Located Features

97 Rna Seq Results