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Gene : HYAL3 Homo sapiens

Name  ? hyaluronidase 3 Cytological Location  3p21.31
Brief Description  hyaluronidase 3
Description  This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]
  • synonyms:
  • LUCA3,
  • LUCA-3,
  • OTTHUMG00000156936,
  • AF040710,
  • hyaluronoglucosaminidase 3,
  • Minna14,
  • HYAL-3,
  • uc003czd.3,
  • LUCA14,
  • NM_003549,
  • HGNC:5322,
  • LUCA-3,
  • HYAL3
  • identifiers:
  • 8372,
  • ENSG00000186792,
  • HYAL3

Genome feature

Region: gene ? Length: 6574  
Location: 3:50292832-50299405 reverse strand Cyto location: 3p21.31

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3753 SN Ps

5 Cross References

15 Data Sets

4 Homologues

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97 Rna Seq Results