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Gene : ATG10 Homo sapiens

Name  ? autophagy related 10 Cytological Location  5q14.1-q14.2
Brief Description  autophagy related 10
Description  Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]
  • synonyms:
  • DKFZP586I0418,
  • uc003khr.5,
  • NM_001131028,
  • ATG10 autophagy related 10 homolog (S. cerevisiae),
  • APG10,
  • APG10L,
  • APG10 autophagy 10-like (S. cerevisiae),
  • OTTHUMG00000119041,
  • ATG10,
  • pp12616,
  • HGNC:20315,
  • APG10L,
  • AK024016,
  • FLJ13954
  • identifiers:
  • 83734,
  • ENSG00000152348,
  • ATG10

Genome feature

Region: gene ? Length: 286482  
Location: 5:81972021-82258502 Cyto location: 5q14.1-q14.2


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Function

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2 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

2 Pathways

3756 SN Ps

5 Cross References

16 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results