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Gene : CASP6 Homo sapiens

Name  ? caspase 6 Cytological Location  4q25
Brief Description  caspase 6
Description  This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015]
  • synonyms:
  • NM_001226,
  • U20536,
  • HGNC:1507,
  • OTTHUMG00000131914,
  • caspase 6, apoptosis-related cysteine protease,
  • caspase 6, apoptosis-related cysteine peptidase,
  • MCH2,
  • MCH2,
  • uc003hzn.2,
  • CASP6
  • identifiers:
  • 839,
  • ENSG00000138794,
  • CASP6

Genome feature

Region: gene ? Length: 14818  
Location: 4:109688628-109703445 reverse strand Cyto location: 4q25


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

3756 SN Ps

5 Cross References

17 Data Sets

21 Homologues

0 Located Features

97 Rna Seq Results