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Gene : CASP7 Homo sapiens

Name  ? caspase 7 Cytological Location  10q25.3
Brief Description  caspase 7
Description  This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  • synonyms:
  • caspase 7, apoptosis-related cysteine peptidase,
  • uc010qsa.4,
  • CMH-1,
  • LICE2,
  • MCH3,
  • CASP7,
  • OTTHUMG00000019076,
  • caspase 7, apoptosis-related cysteine protease,
  • CMH-1,
  • MCH3,
  • ICE-LAP3,
  • HGNC:1508,
  • ICE-LAP3,
  • U37448,
  • CASP-7,
  • NM_033338
  • identifiers:
  • 840,
  • ENSG00000165806,
  • CASP7

Genome feature

Region: gene ? Length: 51748  
Location: 10:113679162-113730909 Cyto location: 10q25.3

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Gene -> HPO annotation (Human Phenotype Ontology)

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Gene --> Proteins.


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3756 SN Ps

5 Cross References

17 Data Sets

17 Homologues

0 Located Features

97 Rna Seq Results