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Function
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49 Pathways
- Activation, myristolyation of BID and translocation to mitochondria,
- Death Receptor Signalling,
- TNFR1-induced proapoptotic signaling,
- Huntington's disease,
- NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10,
- TNF signaling,
- Apoptotic cleavage of cellular proteins,
- CLEC7A (Dectin-1) signaling,
- Programmed Cell Death,
- Toll-like Receptor Cascades,
- p53 signaling pathway,
- Pathways in cancer,
- Apoptosis,
- Dimerization of procaspase-8,
- Viral myocarditis,
- Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways,
- TRAIL signaling,
- Signal Transduction,
- Toxoplasmosis,
- DDX58/IFIH1-mediated induction of interferon-alpha/beta,
- Apoptotic execution phase,
- Regulation of necroptotic cell death,
- Regulation of TNFR1 signaling,
- RIG-I-like receptor signaling pathway,
- Toll-like receptor signaling pathway,
- Toll Like Receptor 4 (TLR4) Cascade,
- Innate Immune System,
- NOD1/2 Signaling Pathway,
- Intrinsic Pathway for Apoptosis,
- Caspase-mediated cleavage of cytoskeletal proteins,
- TRIF(TICAM1)-mediated TLR4 signaling ,
- Alzheimer's disease,
- Apoptosis,
- NOD-like receptor signaling pathway,
- C-type lectin receptors (CLRs),
- FasL/ CD95L signaling,
- Chagas disease American trypanosomiasis,
- Caspase activation via extrinsic apoptotic signalling pathway,
- RIPK1-mediated regulated necrosis,
- CASP8 activity is inhibited,
- Immune System,
- Toll Like Receptor 3 (TLR3) Cascade,
- TLR3-mediated TICAM1-dependent programmed cell death,
- MyD88-independent TLR4 cascade ,
- Caspase activation via Death Receptors in the presence of ligand,
- Regulated Necrosis,
- Regulation by c-FLIP,
- CLEC7A/inflammasome pathway,
- TRIF-mediated programmed cell death
Gene --> GO terms.
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Genomics
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Gene --> Chromosomal location.
Gene --> GO terms.
Gene --> Overlapping genes.
Disease
Gene (Hum OR Rat) --> Mouse Allele (Phenotype)
Gene --> Alleles and Disease (clinVar data)
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Other
49 Pathways
- Activation, myristolyation of BID and translocation to mitochondria,
- Death Receptor Signalling,
- TNFR1-induced proapoptotic signaling,
- Huntington's disease,
- NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10,
- TNF signaling,
- Apoptotic cleavage of cellular proteins,
- CLEC7A (Dectin-1) signaling,
- Programmed Cell Death,
- Toll-like Receptor Cascades,
- p53 signaling pathway,
- Pathways in cancer,
- Apoptosis,
- Dimerization of procaspase-8,
- Viral myocarditis,
- Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways,
- TRAIL signaling,
- Signal Transduction,
- Toxoplasmosis,
- DDX58/IFIH1-mediated induction of interferon-alpha/beta,
- Apoptotic execution phase,
- Regulation of necroptotic cell death,
- Regulation of TNFR1 signaling,
- RIG-I-like receptor signaling pathway,
- Toll-like receptor signaling pathway,
- Toll Like Receptor 4 (TLR4) Cascade,
- Innate Immune System,
- NOD1/2 Signaling Pathway,
- Intrinsic Pathway for Apoptosis,
- Caspase-mediated cleavage of cytoskeletal proteins,
- TRIF(TICAM1)-mediated TLR4 signaling ,
- Alzheimer's disease,
- Apoptosis,
- NOD-like receptor signaling pathway,
- C-type lectin receptors (CLRs),
- FasL/ CD95L signaling,
- Chagas disease American trypanosomiasis,
- Caspase activation via extrinsic apoptotic signalling pathway,
- RIPK1-mediated regulated necrosis,
- CASP8 activity is inhibited,
- Immune System,
- Toll Like Receptor 3 (TLR3) Cascade,
- TLR3-mediated TICAM1-dependent programmed cell death,
- MyD88-independent TLR4 cascade ,
- Caspase activation via Death Receptors in the presence of ligand,
- Regulated Necrosis,
- Regulation by c-FLIP,
- CLEC7A/inflammasome pathway,
- TRIF-mediated programmed cell death
