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Gene : CARD11 Homo sapiens

Name  ? caspase recruitment domain family member 11 Cytological Location  7p22.2
Brief Description  caspase recruitment domain family member 11
Description  The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]
  • synonyms:
  • BIMP3,
  • CARMA1,
  • PPBL,
  • bcl10-interacting maguk protein 3,
  • card-maguk protein 1,
  • BIMP3,
  • OTTHUMG00000023023,
  • HGNC:16393,
  • NM_032415,
  • uc003smv.5,
  • caspase recruitment domain family, member 11,
  • BENTA,
  • CARMA1,
  • IMD11,
  • CARD11,
  • AF322641,
  • IMD11A
  • identifiers:
  • 84433,
  • ENSG00000198286,
  • CARD11

Genome feature

Region: gene ? Length: 137793  
Location: 7:2906075-3043867 reverse strand Cyto location: 7p22.2

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3 Diseases

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259 SN Ps

5 Cross References

19 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results