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Gene : CUL4B Homo sapiens

Name  ? cullin 4B Cytological Location  Xq24
Brief Description  cullin 4B
Description  This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • MRXS15,
  • OTTHUMG00000022302,
  • U58091,
  • MRXSC,
  • NM_003588,
  • CUL-4B,
  • HGNC:2555,
  • CUL4B,
  • MRXHF2,
  • SFM2,
  • uc004esw.4
  • identifiers:
  • 8450,
  • ENSG00000158290,
  • CUL4B

Genome feature

Region: gene ? Length: 51675  
Location: X:120523858-120575532 reverse strand Cyto location: Xq24

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

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Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



495 SNPs

5 Cross References

18 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results