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Function
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96 Pathways
- Signaling by NOTCH1,
- Circadian Clock,
- Iron uptake and transport,
- Cell Cycle, Mitotic,
- Toll Like Receptor 3 (TLR3) Cascade,
- Toll Like Receptor 7/8 (TLR7/8) Cascade,
- Neddylation,
- Disease,
- Downstream signaling events of B Cell Receptor (BCR),
- APC/C-mediated degradation of cell cycle proteins,
- Interleukin-1 signaling,
- MyD88 dependent cascade initiated on endosome,
- Toll Like Receptor 4 (TLR4) Cascade,
- Immune System,
- Dectin-1 mediated noncanonical NF-kB signaling,
- Toll Like Receptor 9 (TLR9) Cascade,
- Toll Like Receptor TLR1:TLR2 Cascade,
- SCF(Skp2)-mediated degradation of p27/p21,
- SCF-beta-TrCP mediated degradation of Emi1,
- Signaling by WNT,
- Toll Like Receptor 2 (TLR2) Cascade,
- Interleukin-17 signaling,
- GLI3 is processed to GLI3R by the proteasome,
- Toll Like Receptor 5 (TLR5) Cascade,
- Signaling by the B Cell Receptor (BCR),
- Transport of small molecules,
- Synthesis of DNA,
- Regulation of APC/C activators between G1/S and early anaphase,
- Regulation of PLK1 Activity at G2/M Transition,
- G2/M Transition,
- TNFR2 non-canonical NF-kB pathway,
- Interleukin-1 family signaling,
- Fc epsilon receptor (FCERI) signaling,
- Post-translational protein modification,
- Cyclin E associated events during G1/S transition ,
- Signaling by Interleukins,
- Prolactin receptor signaling,
- S Phase,
- MAP3K8 (TPL2)-dependent MAPK1/3 activation,
- Cytokine Signaling in Immune system,
- Signaling by NOTCH1 PEST Domain Mutants in Cancer,
- Hedgehog 'off' state,
- Signaling by NOTCH4,
- Degradation of GLI2 by the proteasome,
- Regulation of RUNX2 expression and activity,
- TCR signaling,
- Downstream TCR signaling,
- Diseases of signal transduction by growth factor receptors and second messengers,
- Cyclin A:Cdk2-associated events at S phase entry,
- Signal Transduction,
- Signaling by Hedgehog,
- Toll Like Receptor 10 (TLR10) Cascade,
- CLEC7A (Dectin-1) signaling,
- MAP kinase activation,
- Negative regulation of NOTCH4 signaling,
- NIK-->noncanonical NF-kB signaling,
- Mitotic G1 phase and G1/S transition,
- RNA Polymerase II Transcription,
- Adaptive Immune System,
- Gene expression (Transcription),
- Signaling by NOTCH,
- Antigen processing: Ubiquitination & Proteasome degradation,
- FCERI mediated NF-kB activation,
- MyD88-independent TLR4 cascade ,
- Switching of origins to a post-replicative state,
- NOTCH1 Intracellular Domain Regulates Transcription,
- Cell Cycle,
- Activation of NF-kappaB in B cells,
- C-type lectin receptors (CLRs),
- TRIF(TICAM1)-mediated TLR4 signaling ,
- Signaling by NOTCH1 in Cancer,
- Mitotic G2-G2/M phases,
- Regulation of mitotic cell cycle,
- Generic Transcription Pathway,
- Degradation of GLI1 by the proteasome,
- G1 Phase,
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation,
- Constitutive Signaling by NOTCH1 PEST Domain Mutants,
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants,
- G1/S Transition,
- DNA Replication,
- Toll Like Receptor TLR6:TLR2 Cascade,
- Degradation of beta-catenin by the destruction complex,
- Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling,
- FBXL7 down-regulates AURKA during mitotic entry and in early mitosis,
- Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer,
- MyD88 cascade initiated on plasma membrane,
- Transcriptional regulation by RUNX2,
- FBXW7 Mutants and NOTCH1 in Cancer,
- Class I MHC mediated antigen processing & presentation,
- Innate Immune System,
- Toll-like Receptor Cascades,
- Metabolism of proteins,
- Orc1 removal from chromatin,
- Cyclin D associated events in G1,
- MyD88:MAL(TIRAP) cascade initiated on plasma membrane
Gene --> GO terms.
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Genomics
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Disease
Gene (Hum OR Rat) --> Mouse Allele (Phenotype)
Gene --> Alleles and Disease (clinVar data)
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Other
96 Pathways
- Signaling by NOTCH1,
- Circadian Clock,
- Iron uptake and transport,
- Cell Cycle, Mitotic,
- Toll Like Receptor 3 (TLR3) Cascade,
- Toll Like Receptor 7/8 (TLR7/8) Cascade,
- Neddylation,
- Disease,
- Downstream signaling events of B Cell Receptor (BCR),
- APC/C-mediated degradation of cell cycle proteins,
- Interleukin-1 signaling,
- MyD88 dependent cascade initiated on endosome,
- Toll Like Receptor 4 (TLR4) Cascade,
- Immune System,
- Dectin-1 mediated noncanonical NF-kB signaling,
- Toll Like Receptor 9 (TLR9) Cascade,
- Toll Like Receptor TLR1:TLR2 Cascade,
- SCF(Skp2)-mediated degradation of p27/p21,
- SCF-beta-TrCP mediated degradation of Emi1,
- Signaling by WNT,
- Toll Like Receptor 2 (TLR2) Cascade,
- Interleukin-17 signaling,
- GLI3 is processed to GLI3R by the proteasome,
- Toll Like Receptor 5 (TLR5) Cascade,
- Signaling by the B Cell Receptor (BCR),
- Transport of small molecules,
- Synthesis of DNA,
- Regulation of APC/C activators between G1/S and early anaphase,
- Regulation of PLK1 Activity at G2/M Transition,
- G2/M Transition,
- TNFR2 non-canonical NF-kB pathway,
- Interleukin-1 family signaling,
- Fc epsilon receptor (FCERI) signaling,
- Post-translational protein modification,
- Cyclin E associated events during G1/S transition ,
- Signaling by Interleukins,
- Prolactin receptor signaling,
- S Phase,
- MAP3K8 (TPL2)-dependent MAPK1/3 activation,
- Cytokine Signaling in Immune system,
- Signaling by NOTCH1 PEST Domain Mutants in Cancer,
- Hedgehog 'off' state,
- Signaling by NOTCH4,
- Degradation of GLI2 by the proteasome,
- Regulation of RUNX2 expression and activity,
- TCR signaling,
- Downstream TCR signaling,
- Diseases of signal transduction by growth factor receptors and second messengers,
- Cyclin A:Cdk2-associated events at S phase entry,
- Signal Transduction,
- Signaling by Hedgehog,
- Toll Like Receptor 10 (TLR10) Cascade,
- CLEC7A (Dectin-1) signaling,
- MAP kinase activation,
- Negative regulation of NOTCH4 signaling,
- NIK-->noncanonical NF-kB signaling,
- Mitotic G1 phase and G1/S transition,
- RNA Polymerase II Transcription,
- Adaptive Immune System,
- Gene expression (Transcription),
- Signaling by NOTCH,
- Antigen processing: Ubiquitination & Proteasome degradation,
- FCERI mediated NF-kB activation,
- MyD88-independent TLR4 cascade ,
- Switching of origins to a post-replicative state,
- NOTCH1 Intracellular Domain Regulates Transcription,
- Cell Cycle,
- Activation of NF-kappaB in B cells,
- C-type lectin receptors (CLRs),
- TRIF(TICAM1)-mediated TLR4 signaling ,
- Signaling by NOTCH1 in Cancer,
- Mitotic G2-G2/M phases,
- Regulation of mitotic cell cycle,
- Generic Transcription Pathway,
- Degradation of GLI1 by the proteasome,
- G1 Phase,
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation,
- Constitutive Signaling by NOTCH1 PEST Domain Mutants,
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants,
- G1/S Transition,
- DNA Replication,
- Toll Like Receptor TLR6:TLR2 Cascade,
- Degradation of beta-catenin by the destruction complex,
- Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling,
- FBXL7 down-regulates AURKA during mitotic entry and in early mitosis,
- Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer,
- MyD88 cascade initiated on plasma membrane,
- Transcriptional regulation by RUNX2,
- FBXW7 Mutants and NOTCH1 in Cancer,
- Class I MHC mediated antigen processing & presentation,
- Innate Immune System,
- Toll-like Receptor Cascades,
- Metabolism of proteins,
- Orc1 removal from chromatin,
- Cyclin D associated events in G1,
- MyD88:MAL(TIRAP) cascade initiated on plasma membrane
