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Gene : COX4I2 Homo sapiens

Name  ? cytochrome c oxidase subunit 4I2 Cytological Location  20q11.21
Brief Description  cytochrome c oxidase subunit 4I2
Description  Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008]
  • synonyms:
  • COX4-2,
  • COX4,
  • uc002wwj.2,
  • cytochrome c oxidase subunit IV-like 2,
  • cytochrome c oxidase subunit IV isoform 2 (lung),
  • HGNC:16232,
  • COXIV-2,
  • COX4L2,
  • COX4B,
  • cytochrome c oxidase subunit IV isoform 2,
  • COX4-2,
  • COXIV-2,
  • OTTHUMG00000032180,
  • COX4I2,
  • AF257180,
  • COX4L2,
  • NM_032609,
  • dJ857M17.2,
  • dJ857M17.2,
  • COX4B
  • identifiers:
  • 84701,
  • ENSG00000131055,
  • COX4I2

Genome feature

Region: gene ? Length: 7154  
Location: 20:31637856-31645009 Cyto location: 20q11.21


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

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Gene --> GO terms.

 

Other

0 Pathways

3740 SNPs

5 Cross References

17 Data Sets

11 Homologues

0 Located Features

97 Rna Seq Results