help  | about  | cite  | software

Gene : ATG4C Homo sapiens

Name  ? autophagy related 4C cysteine peptidase Cytological Location  1p31.3
Brief Description  autophagy related 4C cysteine peptidase
Description  Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000009142,
  • autophagy related 4C, cysteine peptidase,
  • APG4 autophagy 4 homolog C (S. cerevisiae),
  • AUTL1,
  • HGNC:16040,
  • AUTL3,
  • NM_032852,
  • APG4C,
  • AUT (S. cerevisiae)-like 1, cysteine endopeptidase; AUT-like 1, cysteine endopeptidase (S. cerevisiae),
  • AUTL3,
  • AUTL1,
  • APG4-C,
  • uc001dat.5,
  • APG4C,
  • FLJ14867,
  • ATG4C,
  • AK027773,
  • ATG4 autophagy related 4 homolog C (S. cerevisiae)
  • identifiers:
  • 84938,
  • ENSG00000125703,
  • ATG4C

Genome feature

Region: gene ? Length: 81752  
Location: 1:62783765-62865516 Cyto location: 1p31.3


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

3756 SN Ps

5 Cross References

15 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results