help  | about  | cite  | software

Gene : ATG4C Homo sapiens

Name  ? autophagy related 4C cysteine peptidase Cytological Location  1p31.3
Brief Description  autophagy related 4C cysteine peptidase
Description  Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008]
  • synonyms:
  • AUT (S. cerevisiae)-like 1, cysteine endopeptidase; AUT-like 1, cysteine endopeptidase (S. cerevisiae),
  • AUTL1,
  • APG4C,
  • AUTL3,
  • ATG4 autophagy related 4 homolog C (S. cerevisiae),
  • HGNC:16040,
  • autophagy related 4C, cysteine peptidase,
  • APG4C,
  • AUTL3,
  • AK027773,
  • NM_032852,
  • ATG4C,
  • OTTHUMG00000009142,
  • uc001dat.5,
  • FLJ14867,
  • APG4-C,
  • AUTL1,
  • APG4 autophagy 4 homolog C (S. cerevisiae)
  • identifiers:
  • 84938,
  • ENSG00000125703,
  • ATG4C

Genome feature

Region: gene ? Length: 81752  
Location: 1:62783765-62865516 Cyto location: 1p31.3

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

2 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



2 Pathways

3740 SN Ps

5 Cross References

14 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results