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Gene : ATG4D Homo sapiens

Name  ? autophagy related 4D cysteine peptidase Cytological Location  19p13.2
Brief Description  autophagy related 4D cysteine peptidase
Description  Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  • synonyms:
  • AJ312332,
  • ATG4D,
  • APG4D,
  • APG4D,
  • uc002mov.5,
  • NM_032885,
  • autophagy related 4D, cysteine peptidase,
  • APG4 autophagy 4 homolog D (S. cerevisiae),
  • AUTL4,
  • HGNC:20789,
  • AUT-like 4, cysteine endopeptidase (S. cerevisiae),
  • AUTL4,
  • OTTHUMG00000180582,
  • APG4-D,
  • APG4-D,
  • ATG4 autophagy related 4 homolog D (S. cerevisiae)
  • identifiers:
  • 84971,
  • ENSG00000130734,
  • ATG4D

Genome feature

Region: gene ? Length: 9522  
Location: 19:10543897-10553418 Cyto location: 19p13.2


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Disease

0 Diseases

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Other

274 SN Ps

5 Cross References

15 Data Sets

9 Homologues

0 Located Features

97 Rna Seq Results