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Gene : DISP1 Homo sapiens

Name  ? dispatched RND transporter family member 1 Cytological Location  1q41
Brief Description  dispatched RND transporter family member 1
Description  The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq, Jul 2008]
  • synonyms:
  • DISPA,
  • dispatched homolog 1 (Drosophila),
  • DISPA,
  • DISP1,
  • OTTHUMG00000037893,
  • HGNC:19711,
  • AK056569,
  • NM_032890,
  • DKFZP434I0428,
  • MGC16796,
  • uc057prm.1,
  • MGC13130
  • identifiers:
  • 84976,
  • ENSG00000154309,
  • DISP1

Genome feature

Region: gene ? Length: 191482  
Location: 1:222814514-223005995 Cyto location: 1q41


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

3753 SN Ps

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results