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Gene : IKBKG Homo sapiens

Name  ? inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Cytological Location  Xq28
Brief Description  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
Description  This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Mar 2016]
  • synonyms:
  • NEMO,
  • ZC2HC9,
  • IP2,
  • inhibitor of nuclear factor kappa B kinase subunit gamma,
  • FIP3,
  • FIP3,
  • ZC2HC9,
  • IPD2,
  • EDAID1,
  • IP1,
  • AF074382,
  • AMCBX1,
  • IP1,
  • IKK-gamma,
  • IKKAP1,
  • NEMO,
  • uc033fbv.2,
  • FIP-3,
  • IKKG,
  • IKBKG,
  • Fip3p,
  • IP2,
  • IKK-gamma,
  • IP,
  • NM_003639,
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma,
  • incontinentia pigmenti,
  • IMD33,
  • FIP-3,
  • HGNC:5961,
  • OTTHUMG00000024234,
  • Fip3p
  • identifiers:
  • 8517,
  • ENSG00000269335,
  • IKBKG

Genome feature

Region: gene ? Length: 23809  
Location: X:154541238-154565046 Cyto location: Xq28


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Function

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95 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

6 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

95 Pathways

430 SN Ps

5 Cross References

18 Data Sets

4 Homologues

1 Located Features

97 Rna Seq Results