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Gene : H2BC12 Homo sapiens

Name  ? H2B clustered histone 12 Cytological Location  6p22.1
Brief Description  H2B clustered histone 12
Description  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family. The protein encoded is an antimicrobial protein with antibacterial and antifungal activity. Two transcripts that encode the same protein have been identified for this gene, which is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015]
  • synonyms:
  • OTTHUMG00000014473,
  • H2B/S,
  • H2B histone family, member T,
  • H2BFT,
  • H2BC12,
  • histone 1, H2bk,
  • HIST1H2BK,
  • H2BFAiii,
  • HIST1H2BK,
  • NM_080593,
  • histone cluster 1 H2B family member k,
  • H2BK,
  • H2BFT,
  • H2BFAiii,
  • uc063mja.1,
  • HGNC:13954,
  • histone cluster 1, H2bk,
  • AJ223352
  • identifiers:
  • 85236,
  • ENSG00000197903,
  • H2BC12

Genome feature

Region: gene ? Length: 8566  
Location: 6:27138293-27146858 reverse strand Cyto location: 6p22.1

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95 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



95 Pathways

3753 SN Ps

5 Cross References

16 Data Sets

18 Homologues

0 Located Features

97 Rna Seq Results