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Gene : AKR7A2 Homo sapiens

Name  ? aldo-keto reductase family 7 member A2 Cytological Location  1p36.13
Brief Description  aldo-keto reductase family 7 member A2
Description  The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
  • synonyms:
  • uc001bbw.4,
  • AKR7A2,
  • AFAR1,
  • AFB1-AR1,
  • NM_003689,
  • AF026947,
  • AKR7,
  • aflatoxin aldehyde reductase,
  • OTTHUMG00000002522,
  • AFAR,
  • HGNC:389,
  • AFAR
  • identifiers:
  • 8574,
  • ENSG00000053371,
  • AKR7A2

Genome feature

Region: gene ? Length: 9439  
Location: 1:19302708-19312146 reverse strand Cyto location: 1p36.13

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3753 SN Ps

5 Cross References

17 Data Sets

3 Homologues

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97 Rna Seq Results