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Gene : CBFA2T3 Homo sapiens

Name  ? CBFA2/RUNX1 partner transcriptional co-repressor 3 Cytological Location  16q24.3
Brief Description  CBFA2/RUNX1 partner transcriptional co-repressor 3
Description  This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
  • synonyms:
  • HGNC:1537,
  • CBFA2T3,
  • MTGR2,
  • MTGR2,
  • CBFA2/RUNX1 translocation partner 3,
  • RUNX1T3,
  • MTG16,
  • AF052213,
  • core-binding factor, runt domain, alpha subunit 2; translocated to, 3,
  • ETO2,
  • OTTHUMG00000137864,
  • ZMYND4,
  • myeloid translocation gene 8 and 16b,
  • MTG16,
  • NM_005187,
  • ZMYND4,
  • RUNX1T3,
  • ETO2,
  • uc002fmm.3
  • identifiers:
  • 863,
  • ENSG00000129993,
  • CBFA2T3

Genome feature

Region: gene ? Length: 102350  
Location: 16:88874858-88977207 reverse strand Cyto location: 16q24.3


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0 Pathways

731 SN Ps

5 Cross References

16 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results