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Gene : DDX3Y Homo sapiens

Name  ? DEAD-box helicase 3 Y-linked Cytological Location  Yq11.221
Brief Description  DEAD-box helicase 3 Y-linked
Description  The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
  • synonyms:
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked,
  • DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked,
  • DDX3Y,
  • NM_004660,
  • HGNC:2699,
  • uc004fsv.3,
  • OTTHUMG00000036324,
  • DBY,
  • DBY,
  • AF000984,
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome
  • identifiers:
  • 8653,
  • ENSG00000067048,
  • DDX3Y

Genome feature

Region: gene ? Length: 16480  
Location: Y:12903999-12920478 Cyto location: Yq11.221


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0 Pathways

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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0 Pathways

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5 Cross References

15 Data Sets

17 Homologues

0 Located Features

97 Rna Seq Results