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Gene : B4GALT4 Homo sapiens

Name  ? beta-1,4-galactosyltransferase 4 Cytological Location  3q13.32
Brief Description  beta-1,4-galactosyltransferase 4
Description  This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • B4Gal-T4,
  • AF022367,
  • beta4Gal-T4,
  • HGNC:927,
  • B4GALT4,
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4,
  • beta4Gal-T4,
  • NM_003778,
  • OTTHUMG00000159358,
  • uc003eci.4
  • identifiers:
  • 8702,
  • ENSG00000121578,
  • B4GALT4

Genome feature

Region: gene ? Length: 29166  
Location: 3:119211742-119240907 reverse strand Cyto location: 3q13.32


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3756 SN Ps

5 Cross References

17 Data Sets

13 Homologues

0 Located Features

97 Rna Seq Results