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Gene : B4GALT3 Homo sapiens

Name  ? beta-1,4-galactosyltransferase 3 Cytological Location  1q23.3
Brief Description  beta-1,4-galactosyltransferase 3
Description  This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]
  • synonyms:
  • uc001fyr.3,
  • beta4Gal-T3,
  • OTTHUMG00000034348,
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3,
  • B4GALT3,
  • NM_003779,
  • beta4Gal-T3,
  • BC006099,
  • HGNC:926
  • identifiers:
  • 8703,
  • ENSG00000158850,
  • B4GALT3

Genome feature

Region: gene ? Length: 13698  
Location: 1:161171310-161185007 reverse strand Cyto location: 1q23.3


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557 SN Ps

5 Cross References

16 Data Sets

13 Homologues

0 Located Features

97 Rna Seq Results