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Gene : B3GALT4 Homo sapiens

Name  ? beta-1,3-galactosyltransferase 4 Cytological Location  6p21.32
Brief Description  beta-1,3-galactosyltransferase 4
Description  This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is oriented telomere to centromere in close proximity to the ribosomal protein S18 gene. The functionality of the encoded protein is limited to ganglioseries glycolipid biosynthesis. [provided by RefSeq, Jul 2008]
  • synonyms:
  • UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase 4,
  • beta3Gal-T4,
  • BETA3GALT4,
  • B3GALT4,
  • NM_003782,
  • UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4,
  • GALT4,
  • GALT2,
  • Y15061,
  • GalT4,
  • HGNC:919,
  • uc011jag.2,
  • ganglioside galactosyltransferase,
  • OTTHUMG00000031100
  • identifiers:
  • 8705,
  • ENSG00000235863,
  • B3GALT4

Genome feature

Region: gene ? Length: 1703  
Location: 6:33277123-33278825 Cyto location: 6p21.32


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615 SN Ps

5 Cross References

15 Data Sets

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97 Rna Seq Results