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Gene : EED Homo sapiens

Name  ? embryonic ectoderm development Cytological Location  11q14.2
Brief Description  embryonic ectoderm development
Description  This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000167209,
  • NM_003797,
  • WAIT1,
  • HEED,
  • COGIS,
  • HGNC:3188,
  • WD protein associating with integrin cytoplasmic tails 1,
  • WAIT-1,
  • EED,
  • AF078933,
  • uc001pbp.4,
  • HEED
  • identifiers:
  • 8726,
  • ENSG00000074266,
  • EED

Genome feature

Region: gene ? Length: 41037  
Location: 11:86244384-86285420 Cyto location: 11q14.2

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

19 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results