help  | about  | cite  | software

Gene : CRADD Homo sapiens

Name  ? CASP2 and RIPK1 domain containing adaptor with death domain Cytological Location  12q22
Brief Description  CASP2 and RIPK1 domain containing adaptor with death domain
Description  This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
  • synonyms:
  • CRADD,
  • HGNC:2340,
  • NM_003805,
  • RIP-associated ICH1/CED3-homologous protein with death domain,
  • RAIDD,
  • MRT34,
  • U84388,
  • OTTHUMG00000170322,
  • RAIDD,
  • uc001tda.4
  • identifiers:
  • 8738,
  • ENSG00000169372,
  • CRADD

Genome feature

Region: gene ? Length: 217499  
Location: 12:93677342-93894840 Cyto location: 12q22


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

150 SN Ps

5 Cross References

19 Data Sets

4 Homologues

5 Located Features

97 Rna Seq Results