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Gene : DLK1 Homo sapiens

Name  ? delta like non-canonical Notch ligand 1 Cytological Location  14q32.2
Brief Description  delta like non-canonical Notch ligand 1
Description  This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015]
  • synonyms:
  • Pref-1,
  • U15979,
  • ZOG,
  • OTTHUMG00000171600,
  • PREF1,
  • FA1,
  • pG2,
  • FA1,
  • ZOG,
  • delta-like 1 homolog (Drosophila),
  • delta-like homolog (Drosophila),
  • DLK,
  • NM_001317172,
  • Delta1,
  • pG2,
  • HGNC:2907,
  • Delta1,
  • Pref-1,
  • DLK1,
  • uc001yhs.5,
  • DLK-1
  • identifiers:
  • 8788,
  • ENSG00000185559,
  • DLK1

Genome feature

Region: gene ? Length: 11333  
Location: 14:100726892-100738224 Cyto location: 14q32.2

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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353 SN Ps

5 Cross References

17 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results