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Gene : APLN Homo sapiens

Name  ? apelin Cytological Location  Xq26.1
Brief Description  apelin
Description  This gene encodes a peptide that functions as an endogenous ligand for the G-protein coupled apelin receptor. The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments. These peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. [provided by RefSeq, Feb 2016]
  • synonyms:
  • apelin,
  • XNPEP2,
  • AF179680,
  • NM_017413,
  • APLN,
  • XNPEP2,
  • uc004eus.4,
  • OTTHUMG00000022371,
  • HGNC:16665,
  • APEL,
  • apelin, AGTRL1 ligand
  • identifiers:
  • 8862,
  • ENSG00000171388,
  • APLN

Genome feature

Region: gene ? Length: 9698  
Location: X:129645259-129654956 reverse strand Cyto location: Xq26.1

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Gene -> HPO annotation (Human Phenotype Ontology)

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



241 SNPs

5 Cross References

13 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results