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Gene : CDC16 Homo sapiens

Name  ? cell division cycle 16 Cytological Location  13q34
Brief Description  cell division cycle 16
Description  The protein encoded by this gene functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex. The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation by the 26S proteasome. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein, and other APC complex proteins, contain a tetratricopeptide repeat (TPR) domain; a protein domain that is often involved in protein-protein interactions and the assembly of multiprotein complexes. Multiple alternatively spliced transcript variants, encoding distinct proteins, have been identified. [provided by RefSeq, Jan 2016]
  • synonyms:
  • APC6,
  • CDC16Hs,
  • cell division cycle 16 homolog (S. cerevisiae),
  • uc001vuk.1,
  • HGNC:1720,
  • CDC16,
  • ANAPC6,
  • CDC16 cell division cycle 16 homolog (S. cerevisiae),
  • OTTHUMG00000017402,
  • NM_003903,
  • anaphase-promoting complex, subunit 6,
  • CUT9,
  • U18291,
  • CDC16 (cell division cycle 16, S. cerevisiae, homolog),
  • CUT9,
  • APC6,
  • ANAPC6
  • identifiers:
  • 8881,
  • ENSG00000130177,
  • CDC16

Genome feature

Region: gene ? Length: 37879  
Location: 13:114234845-114272723 Cyto location: 13q34


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Function

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45 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

45 Pathways

3753 SN Ps

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results