help  | about  | cite  | software

Gene : AP1S2 Homo sapiens

Name  ? adaptor related protein complex 1 subunit sigma 2 Cytological Location  Xp22.2
Brief Description  adaptor related protein complex 1 subunit sigma 2
Description  Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]
  • synonyms:
  • PGS,
  • adaptor related protein complex 1 sigma 2 subunit,
  • MRXS5,
  • MRX59,
  • mental retardation, X-linked, syndromic 5,
  • Pettigrew X-linked mental retardation syndrome,
  • mental retardation, X-linked 59,
  • OTTHUMG00000021186,
  • AB015320,
  • PGS,
  • SIGMA1B,
  • DC22,
  • NM_003916,
  • MRXS5,
  • uc004cxi.5,
  • MRX59,
  • HGNC:560,
  • MRXSF,
  • MRXS21,
  • SIGMA1B,
  • AP1S2
  • identifiers:
  • 8905,
  • ENSG00000182287,
  • AP1S2

Genome feature

Region: gene ? Length: 29161  
Location: X:15825806-15854966 reverse strand Cyto location: Xp22.2

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SNPs

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results