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Gene : CHRFAM7A Homo sapiens

Name  ? CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion Cytological Location  15q13.2
Brief Description  CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion
Description  The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CHRFAM7A,
  • CHRNA7,
  • D-10,
  • CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion,
  • D-10,
  • OTTHUMG00000175645,
  • uc001zdt.2,
  • CHRNA7-DR1,
  • NACHRA7,
  • CHRNA7-DR1,
  • NM_148911,
  • HGNC:15781,
  • AF029838
  • identifiers:
  • 89832,
  • ENSG00000166664,
  • CHRFAM7A

Genome feature

Region: gene ? Length: 33284  
Location: 15:30360566-30393849 reverse strand Cyto location: 15q13.2


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3753 SN Ps

4 Cross References

13 Data Sets

30 Homologues

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97 Rna Seq Results