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Gene : DOK2 Homo sapiens

Name  ? docking protein 2 Cytological Location  8p21.3
Brief Description  docking protein 2
Description  The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]
  • synonyms:
  • DOK2,
  • OTTHUMG00000131075,
  • HGNC:2991,
  • NM_003974,
  • downstream of tyrosine kinase 2,
  • p56DOK,
  • AF034970,
  • p56dok-2,
  • uc003wzy.2,
  • docking protein 2, 56kDa,
  • p56dok-2,
  • Dok-2,
  • docking protein 2, 56kD
  • identifiers:
  • 9046,
  • ENSG00000147443,
  • DOK2

Genome feature

Region: gene ? Length: 4845  
Location: 8:21908873-21913717 reverse strand Cyto location: 8p21.3


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

186 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results