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Gene : PAPSS2 Homo sapiens

Name  ? 3'-phosphoadenosine 5'-phosphosulfate synthase 2 Cytological Location  10q23.2-q23.31
Brief Description  3'-phosphoadenosine 5'-phosphosulfate synthase 2
Description  Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • ATPSK2,
  • ATPSK2,
  • AF091242,
  • adenylyl-sulfate kinase,
  • PAPSS2,
  • sulfate adenylyltransferase,
  • uc001kex.4,
  • OTTHUMG00000018683,
  • BCYM4,
  • SK2,
  • adenosine 5'-phosphosulfate kinase,
  • NM_001015880,
  • bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2,
  • HGNC:8604
  • identifiers:
  • 9060,
  • ENSG00000198682,
  • PAPSS2

Genome feature

Region: gene ? Length: 87828  
Location: 10:87659878-87747705 Cyto location: 10q23.2-q23.31

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1 Diseases

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3740 SN Ps

5 Cross References

19 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results