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Gene : PAPSS1 Homo sapiens

Name  ? 3'-phosphoadenosine 5'-phosphosulfate synthase 1 Cytological Location  4q25
Brief Description  3'-phosphoadenosine 5'-phosphosulfate synthase 1
Description  Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 [PubMed 10679223]). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (MIM 603005).[supplied by OMIM, Mar 2008]
  • synonyms:
  • PAPSS,
  • Y10387,
  • OTTHUMG00000131210,
  • NM_005443,
  • PAPSS1,
  • HGNC:8603,
  • PAPSS,
  • ATPSK1,
  • SK1,
  • uc003hyk.4,
  • ATPSK1,
  • sulfate adenylyltransferase,
  • adenylyl-sulfate kinase
  • identifiers:
  • 9061,
  • ENSG00000138801,
  • PAPSS1

Genome feature

Region: gene ? Length: 106569  
Location: 4:107613666-107720234 reverse strand Cyto location: 4q25

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SNPs

5 Cross References

15 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results