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Gene : CLDN10 Homo sapiens

Name  ? claudin 10 Cytological Location  13q32.1
Brief Description  claudin 10
Description  This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.[provided by RefSeq, Jun 2010]
  • synonyms:
  • OSP-L,
  • CLDN10,
  • HGNC:2033,
  • CPETRL3,
  • OSP-L,
  • HELIX,
  • U89916,
  • OSPL,
  • OTTHUMG00000017217,
  • CPETRL3,
  • NM_006984,
  • uc001vmh.3
  • identifiers:
  • 9071,
  • ENSG00000134873,
  • CLDN10

Genome feature

Region: gene ? Length: 146172  
Location: 13:95433588-95579759 Cyto location: 13q32.1


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

3753 SN Ps

5 Cross References

19 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results