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Gene : CLDN6 Homo sapiens

Name  ? claudin 6 Cytological Location  16p13.3
Brief Description  claudin 6
Description  Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]
  • synonyms:
  • AJ249735,
  • uc002csu.5,
  • NM_021195,
  • HGNC:2048,
  • CLDN6,
  • OTTHUMG00000128999
  • identifiers:
  • 9074,
  • ENSG00000184697,
  • CLDN6

Genome feature

Region: gene ? Length: 3472  
Location: 16:3014712-3018183 reverse strand Cyto location: 16p13.3


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

38 SN Ps

5 Cross References

15 Data Sets

15 Homologues

0 Located Features

97 Rna Seq Results