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Gene : CLDN1 Homo sapiens

Name  ? claudin 1 Cytological Location  3q28
Brief Description  claudin 1
Description  Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]
  • synonyms:
  • HGNC:2032,
  • AF101051,
  • ILVASC,
  • SEMP1,
  • NM_021101,
  • CLDN1,
  • uc003fsh.4,
  • ILVASC,
  • senescence-associated epithelial membrane protein 1,
  • SEMP1,
  • CLD1,
  • OTTHUMG00000156214
  • identifiers:
  • 9076,
  • ENSG00000163347,
  • CLDN1

Genome feature

Region: gene ? Length: 16740  
Location: 3:190305707-190322446 reverse strand Cyto location: 3q28


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Proteins

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SNPs

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Disease

1 Diseases

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Expression

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Other

3753 SN Ps

5 Cross References

19 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results