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Gene : DIRAS3 Homo sapiens

Name  ? DIRAS family GTPase 3 Cytological Location  1p31.3
Brief Description  DIRAS family GTPase 3
Description  This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex. [provided by RefSeq, Nov 2015]
  • synonyms:
  • OTTHUMG00000009544,
  • uc001ded.4,
  • NOEY2,
  • DIRAS3,
  • NOEY2,
  • HGNC:687,
  • ras homolog gene family, member I,
  • ARHI,
  • U96750,
  • DIRAS family, GTP-binding RAS-like 3,
  • ARHI,
  • NM_004675
  • identifiers:
  • 9077,
  • ENSG00000162595,
  • DIRAS3

Genome feature

Region: gene ? Length: 5746  
Location: 1:68045886-68051631 reverse strand Cyto location: 1p31.3

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

600 SN Ps

5 Cross References

15 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results