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Gene : CD1B Homo sapiens

Name  ? CD1b molecule Cytological Location  1q23.1
Brief Description  CD1b molecule
Description  This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CD1B antigen, b polypeptide,
  • OTTHUMG00000017513,
  • M28826,
  • CD1b antigen,
  • R1,
  • CD1,
  • CD1B,
  • CD1A,
  • NM_001764,
  • uc001frx.4,
  • CD1,
  • HGNC:1635
  • identifiers:
  • 910,
  • ENSG00000158485,
  • CD1B

Genome feature

Region: gene ? Length: 46126  
Location: 1:158285406-158331531 reverse strand Cyto location: 1q23.1

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0 Diseases

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Gene -> HPO annotation (Human Phenotype Ontology)

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386 SNPs

5 Cross References

16 Data Sets

21 Homologues

0 Located Features

97 Rna Seq Results