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Gene : CD1D Homo sapiens

Name  ? CD1d molecule Cytological Location  1q23.1
Brief Description  CD1d molecule
Description  This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
  • synonyms:
  • R3,
  • R3G1,
  • BC027926,
  • uc001frr.4,
  • CD1A,
  • NM_001766,
  • OTTHUMG00000022436,
  • CD1D,
  • CD1d antigen,
  • CD1D antigen, d polypeptide,
  • HGNC:1637
  • identifiers:
  • 912,
  • ENSG00000158473,
  • CD1D

Genome feature

Region: gene ? Length: 8398  
Location: 1:158178030-158186427 Cyto location: 1q23.1


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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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Expression

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Other

3753 SN Ps

6 Cross References

17 Data Sets

24 Homologues

0 Located Features

97 Rna Seq Results