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Function
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39 Pathways
- CDK-mediated phosphorylation and removal of Cdc6,
- Cyclin A:Cdk2-associated events at S phase entry,
- Cell Cycle, Mitotic,
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3),
- S Phase,
- Cell Cycle Checkpoints,
- G1/S Transition,
- Aberrant regulation of mitotic cell cycle due to RB1 defects,
- Cyclin E associated events during G1/S transition ,
- DNA Damage/Telomere Stress Induced Senescence,
- G1/S DNA Damage Checkpoints,
- TP53 Regulates Transcription of Cell Cycle Genes,
- Diseases of mitotic cell cycle,
- Switching of origins to a post-replicative state,
- DNA Replication,
- Mitotic G1 phase and G1/S transition,
- Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes,
- Transcriptional Regulation by TP53,
- Cellular responses to stress,
- Disease,
- Cell Cycle,
- Association of TriC/CCT with target proteins during biosynthesis,
- G0 and Early G1,
- Generic Transcription Pathway,
- Chaperonin-mediated protein folding,
- SCF(Skp2)-mediated degradation of p27/p21,
- Cellular responses to external stimuli,
- Metabolism of proteins,
- RNA Polymerase II Transcription,
- p53-Dependent G1 DNA Damage Response,
- Cellular Senescence,
- Synthesis of DNA,
- Gene expression (Transcription),
- p53-Dependent G1/S DNA damage checkpoint,
- Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects,
- Protein folding,
- Cyclin D associated events in G1,
- G1 Phase,
- TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Gene --> GO terms.
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Genomics
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Gene --> Chromosomal location.
Gene --> GO terms.
Gene --> Overlapping genes.
Disease
Gene (Hum OR Rat) --> Mouse Allele (Phenotype)
Gene --> Alleles and Disease (clinVar data)
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Other
39 Pathways
- CDK-mediated phosphorylation and removal of Cdc6,
- Cyclin A:Cdk2-associated events at S phase entry,
- Cell Cycle, Mitotic,
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3),
- S Phase,
- Cell Cycle Checkpoints,
- G1/S Transition,
- Aberrant regulation of mitotic cell cycle due to RB1 defects,
- Cyclin E associated events during G1/S transition ,
- DNA Damage/Telomere Stress Induced Senescence,
- G1/S DNA Damage Checkpoints,
- TP53 Regulates Transcription of Cell Cycle Genes,
- Diseases of mitotic cell cycle,
- Switching of origins to a post-replicative state,
- DNA Replication,
- Mitotic G1 phase and G1/S transition,
- Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes,
- Transcriptional Regulation by TP53,
- Cellular responses to stress,
- Disease,
- Cell Cycle,
- Association of TriC/CCT with target proteins during biosynthesis,
- G0 and Early G1,
- Generic Transcription Pathway,
- Chaperonin-mediated protein folding,
- SCF(Skp2)-mediated degradation of p27/p21,
- Cellular responses to external stimuli,
- Metabolism of proteins,
- RNA Polymerase II Transcription,
- p53-Dependent G1 DNA Damage Response,
- Cellular Senescence,
- Synthesis of DNA,
- Gene expression (Transcription),
- p53-Dependent G1/S DNA damage checkpoint,
- Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects,
- Protein folding,
- Cyclin D associated events in G1,
- G1 Phase,
- TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
