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Gene : DDX60L Homo sapiens

Name  ? DExD/H-box 60 like Cytological Location  4q32.3
Brief Description  DExD/H-box 60 like
Description  This gene encodes a member of the DExD/H-box helicase family of proteins, a subset of the super family 2 helicases. Members of the DExD/H-box helicase family share a conserved functional core comprised of two RecA-like globular domains. These domains contain conserved motifs that mediate ATP binding, ATP hydrolysis, nucleic acid binding, and RNA unwinding. In addition to functions in RNA metabolism, members of this family are involved in anti-viral immunity and act as cytosolic sensors of viral nucleic acids. The protein encoded by this gene has been shown to inhibit hepatitis C virus replication in response to interferon stimulation in cell culture. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
  • synonyms:
  • FLJ31033,
  • HGNC:26429,
  • AK092461,
  • OTTHUMG00000161412,
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like,
  • DDX60L,
  • NM_001012967,
  • uc003irq.5
  • identifiers:
  • 91351,
  • ENSG00000181381,
  • DDX60L

Genome feature

Region: gene ? Length: 123780  
Location: 4:168356735-168480514 reverse strand Cyto location: 4q32.3


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

3753 SN Ps

5 Cross References

16 Data Sets

1 Homologues

0 Located Features

97 Rna Seq Results