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Gene : HGS Homo sapiens

Name  ? hepatocyte growth factor-regulated tyrosine kinase substrate Cytological Location  17q25.3
Brief Description  hepatocyte growth factor-regulated tyrosine kinase substrate
description  The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010]
  • synonyms:
  • HGNC:4897,
  • uc002kbg.4,
  • OTTHUMG00000178109,
  • ZFYVE8,
  • HRS,
  • Vps27,
  • Hrs,
  • NM_004712,
  • HGS,
  • D84064
  • identifiers:
  • 9146,
  • ENSG00000185359,
  • HGS

Genome feature

Region: gene ? Length: 18111  
Location: 17:81684011-81702121 Cyto location: 17q25.3

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Orthologues


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



430 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results