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Gene : CD3D Homo sapiens

Name  ? CD3d molecule Cytological Location  11q23.3
Brief Description  CD3d molecule
Description  The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]
  • synonyms:
  • CD3-DELTA,
  • T3D,
  • CD3D,
  • X01451,
  • uc001pss.2,
  • HGNC:1673,
  • T3D,
  • CD3d antigen, delta polypeptide (TiT3 complex),
  • CD3d molecule, delta (CD3-TCR complex),
  • IMD19,
  • NM_000732,
  • OTTHUMG00000166970
  • identifiers:
  • 915,
  • ENSG00000167286,
  • CD3D

Genome feature

Region: gene ? Length: 3752  
Location: 11:118338954-118342705 reverse strand Cyto location: 11q23.3


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Disease

1 Diseases

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Other

20 SN Ps

5 Cross References

19 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results