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Gene : COX7A2L Homo sapiens

Name  ? cytochrome c oxidase subunit 7A2 like Cytological Location  2p21
Brief Description  cytochrome c oxidase subunit 7A2 like
Description  Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016]
  • synonyms:
  • SIG81,
  • OTTHUMG00000128605,
  • cytochrome c oxidase subunit VIIa polypeptide 2 like,
  • EB1,
  • SIG81,
  • COX7A2L,
  • NM_004718,
  • AB007618,
  • COX7RP,
  • COX7AR,
  • COX7AR,
  • HGNC:2289,
  • uc002rsl.4,
  • COX7RP,
  • EB1
  • identifiers:
  • 9167,
  • ENSG00000115944,
  • COX7A2L

Genome feature

Region: gene ? Length: 33399  
Location: 2:42335559-42368957 reverse strand Cyto location: 2p21


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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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3740 SNPs

5 Cross References

15 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results