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Gene : BMP15 Homo sapiens

Name  ? bone morphogenetic protein 15 Cytological Location  Xp11.22
Brief Description  bone morphogenetic protein 15
Description  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. [provided by RefSeq, Aug 2016]
  • synonyms:
  • OTTHUMG00000021525,
  • HGNC:1068,
  • ODG2,
  • GDF9B,
  • NM_005448,
  • uc011mnw.3,
  • POF4,
  • AF082349,
  • BMP15,
  • GDF9B
  • identifiers:
  • 9210,
  • ENSG00000130385,
  • BMP15

Genome feature

Region: gene ? Length: 5907  
Location: X:50910735-50916641 Cyto location: Xp11.22


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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

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Other

0 SN Ps

5 Cross References

15 Data Sets

40 Homologues

0 Located Features

97 Rna Seq Results