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Gene : GCM2 Homo sapiens

Name  ? glial cells missing transcription factor 2 Cytological Location  6p24.2
Brief Description  glial cells missing transcription factor 2
Description  This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism. [provided by RefSeq, Jul 2008]
  • synonyms:
  • glial cells missing homolog 2 (Drosophila),
  • AF079550,
  • GCMB,
  • NM_004752,
  • glial cells missing (Drosophila) homolog b,
  • HRPT4,
  • hGCMb,
  • HGNC:4198,
  • OTTHUMG00000014249,
  • uc003mzn.5,
  • hGCMb,
  • GCM2,
  • GCMB
  • identifiers:
  • 9247,
  • ENSG00000124827,
  • GCM2

Genome feature

Region: gene ? Length: 8819  
Location: 6:10873223-10882041 reverse strand Cyto location: 6p24.2


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

3 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results