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Gene : CYTH1 Homo sapiens

Name  ? cytohesin 1 Cytological Location  17q25.3
Brief Description  cytohesin 1
Description  The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
  • synonyms:
  • M85169,
  • D17S811E,
  • PSCD1,
  • HGNC:9501,
  • PSCD1,
  • uc002jvw.4,
  • CYTH1,
  • NM_004762,
  • OTTHUMG00000150253,
  • B2-1,
  • D17S811E,
  • cytohesin-1,
  • SEC7,
  • pleckstrin homology, Sec7 and coiled-coil domains 1,
  • B2-1
  • identifiers:
  • 9267,
  • ENSG00000108669,
  • CYTH1

Genome feature

Region: gene ? Length: 108227  
Location: 17:78674047-78782273 reverse strand Cyto location: 17q25.3

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0 Diseases

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3740 SNPs

5 Cross References

15 Data Sets

9 Homologues

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97 Rna Seq Results