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Gene : B4GALT6 Homo sapiens

Name  ? beta-1,4-galactosyltransferase 6 Cytological Location  18q12.1
Brief Description  beta-1,4-galactosyltransferase 6
Description  This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes in human. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. This gene produces multiple protein isoforms - some of which are predicted to lack the N-terminal hydrophobic signal sequence and transmembrane domain. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The canonical enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis. [provided by RefSeq, Jan 2020]
  • synonyms:
  • B4Gal-T6,
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6,
  • B4GALT6,
  • beta4Gal-T6,
  • OTTHUMG00000131980,
  • uc002kwz.5,
  • AF038664,
  • NM_004775,
  • UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase,
  • HGNC:929,
  • beta4GalT-VI
  • identifiers:
  • 9331,
  • ENSG00000118276,
  • B4GALT6

Genome feature

Region: gene ? Length: 102425  
Location: 18:31622246-31724670 reverse strand Cyto location: 18q12.1

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911 SNPs

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results