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Gene : CD163 Homo sapiens

Name  ? CD163 molecule Cytological Location  12p13.31
Brief Description  CD163 molecule
Description  The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
  • synonyms:
  • HGNC:1631,
  • NM_203416,
  • NM_004244,
  • M130,
  • MM130,
  • uc001qsz.4,
  • CD163 antigen,
  • OTTHUMG00000168353,
  • SCARI1,
  • M130,
  • SCARI1,
  • MM130,
  • CD163,
  • Z22968
  • identifiers:
  • 9332,
  • ENSG00000177575,
  • CD163

Genome feature

Region: gene ? Length: 33008  
Location: 12:7470811-7503818 reverse strand Cyto location: 12p13.31


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Disease

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204 SN Ps

5 Cross References

17 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results