help  | about  | cite  | software

Gene : CD163 Homo sapiens

Name  ? CD163 molecule Cytological Location  12p13.31
Brief Description  CD163 molecule
Description  The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
  • synonyms:
  • uc001qsz.4,
  • SCARI1,
  • NM_203416,
  • HGNC:1631,
  • SCARI1,
  • MM130,
  • OTTHUMG00000168353,
  • MM130,
  • Z22968,
  • CD163 antigen,
  • NM_004244,
  • CD163,
  • M130,
  • M130
  • identifiers:
  • 9332,
  • ENSG00000177575,
  • CD163

Genome feature

Region: gene ? Length: 32998  
Location: 12:7470811-7503808 reverse strand Cyto location: 12p13.31

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



204 SN Ps

5 Cross References

17 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results