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Gene : CLEC6A Homo sapiens

Name  ? C-type lectin domain containing 6A Cytological Location  12p13.31
Brief Description  C-type lectin domain containing 6A
Description  The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
  • synonyms:
  • uc001qum.2,
  • HGNC:14556,
  • CLEC4N,
  • CLECSF10,
  • AY321309,
  • dectin-2,
  • C-type lectin domain family 6, member A,
  • CLECSF10,
  • C-type lectin domain family 6 member A,
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10,
  • NM_001007033,
  • OTTHUMG00000168672,
  • CLEC6A,
  • dectin-2
  • identifiers:
  • 93978,
  • ENSG00000205846,
  • CLEC6A

Genome feature

Region: gene ? Length: 22369  
Location: 12:8455962-8478330 Cyto location: 12p13.31


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Disease

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242 SN Ps

4 Cross References

11 Data Sets

21 Homologues

0 Located Features

97 Rna Seq Results