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Gene : DDX23 Homo sapiens

Name  ? DEAD-box helicase 23 Cytological Location  12q13.12
Brief Description  DEAD-box helicase 23
Description  This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • synonyms:
  • DDX23,
  • U5-100KD,
  • AF026402,
  • U5-100K,
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 23,
  • HGNC:17347,
  • NM_004818,
  • SNRNP100,
  • SNRNP100,
  • U5-100K,
  • PRPF28,
  • PRP28 homolog, yeast,
  • prp28,
  • OTTHUMG00000170399,
  • prp28,
  • uc001rsm.4,
  • PRPF28
  • identifiers:
  • 9416,
  • ENSG00000174243,
  • DDX23

Genome feature

Region: gene ? Length: 22408  
Location: 12:48829756-48852163 reverse strand Cyto location: 12q13.12

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0 Diseases

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70 SNPs

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results