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Gene : CD86 Homo sapiens

Name  ? CD86 molecule Cytological Location  3q13.33
Brief Description  CD86 molecule
Description  This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
  • synonyms:
  • B70,
  • LAB72,
  • CD86 antigen (CD28 antigen ligand 2, B7-2 antigen),
  • HGNC:1705,
  • OTTHUMG00000159482,
  • CD28LG2,
  • NM_006889,
  • CD86,
  • B7-2,
  • B-lymphocyte antigen B7-2,
  • B7-2,
  • uc003eet.4,
  • B7.2,
  • CD28LG2,
  • B7.2
  • identifiers:
  • 942,
  • ENSG00000114013,
  • CD86

Genome feature

Region: gene ? Length: 65775  
Location: 3:122055362-122121136 Cyto location: 3q13.33

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407 SNPs

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results